OP88 Drawing Lines In The Sand: How Do We Define The Scope Of Analysis In HTA And Economic Evaluation?

Introduction We explore how the scope of analysis is defined in health technology assessment (HTA) and economic evaluation consider potential implications these decisions. Methods The analysis, including decisions about which methods domains HTA to include assessment, costs, outcomes are most meaningful, comparators relevant typically informed by needs decision-maker. undertook two systematic scoping reviews assess: (i) what extent systems thinking considered literature-based assessments; (ii) using Clostridioides difficile infection as an exemplar. synthesized findings from offer three key observations for future research exploration field HTA. Results Our found that evaluations focus on single interventions, often ignoring upstream downstream interventions. Similarly, published assessments have narrowly inconsistent scopes with limited consideration indirect non-health impacts. Three include: value heath A a intervention may simplify analysis; however, will this siloed decision-making lead optimal resource allocation? inconsistently analysis. decision problem focuses decision-maker practical; inconsistencies perspectives across create unfair conceptualizations value? (iii) technology-focused, not patient-focused. technology-focused system aligns diffusion process; does move us away patient-centered mandate HTA? Conclusions dynamic nature leads many value. Considering defined, inconsistent, analyses consequences achieving high-quality system.